Summary: Identification of selective deubiquitinase (DUB) inhibitors is critical for probe development to further understand and explore DUB biological function.Here, we detail the optimization and deployment houston texans shorts of an in vitro fluorogenic ubiquitin-rhodamine assay to conduct high-throughput screening of a small molecule library a
Assessing the risk of dengue virus transmission in a non-endemic city surrounded by endemic and hyperendemic areas
Objective: To assess the potential risk of dengue transmission in a non-endemic city using a spatial epidemiological approach.Methods: Past dengue exposure of the general population was examined by dengue virus (DENV) IgG testing of archived samples from voluntary blood donors.Vector intensities were determined by local ovitrap index (OI).Analyses